In late 1969, Clapton made the switch to the Fender Stratocaster. "I had a lot of influences when I took up the Strat. First there was Buddy Holly, and Buddy Guy. Hank Marvin was the first well known person over here in England who was using one, but that wasn't really my kind of music. Steve Winwood had so much credibility, and when he started playing one, I thought, oh, if he can do it, I can do it." First was "Brownie" used during the recording of Eric Clapton which in 1974 became the backup to the most famous of all Clapton's guitars, "Blackie." In November 1970 Eric bought six Fender Stratocasters from the Sho-bud guitar shop in Nashville, Tennessee while on tour with the Dominos. He gave one each to George Harrison, Steve Winwood and Pete Townshend.

Clapton assembled the best components of the remaining three to create "Blackie", which was his favourite stage guitar until its retirement in 1985. It was first played live January 13, 1973 at the Rainbow Concert. Clapton called the 1956/57 Strat a "mongrel". On 24 June, 2004, Clapton sold "Blackie" at Christie's Auction House, New York for $959,500 to raise funds for his Crossroads Centre for drug and alcohol addictions. "Brownie" is now on display at the Experience Music Project. The Fender Custom Shop has since produced a limited run of 275 'Blackie' replicas, correct in every detail right down to the 'Duck Brothers' flight case, and artificially aged using Fender's 'Relic' process to simulate years of hard wear. One was presented to Eric upon the model's release.